The signal had implanted specific codes and patterns into their brains at an earlier time - in Isaac Clarke's case, during the events on Aegis VII - and these replication blueprints were extracted and studied via sessions in the NoonTech Diagnostic Machine, using a needle through the ocular cavity into the patient's brain.

The team used the information stored in the minds of Isaac Clarke, Nolan Stross and at least three others (Clarke and Stross were called Patient Four and Patient Five, respectively) suffering from mental illness from a Marker's signal as the basis for their research. Many details regarding the construction process remain a mystery, but various logs suggested that the Marker was 'grown' from mineral printing baths layer by layer, using heuristic algorithms as blueprints. According to one of Tiedemann's logs, those involved with the project had come to the consensus that humanity could no longer sustain itself and that EarthGov needed to study the Markers in order to secure new sources of energy. The Site 12 Marker was built by a team of scientists and engineers stationed on Titan Station under the orders of Director Tiedemann during Project Telomere. The Marker-touched parts of Isaac's brain are stimulated through the NoonTech Diagnostic Machine. I spent years sifting through your demented brain!' - Hans Tiedemann to Isaac Clarke about the Marker's creation. History Construction ' I knew you were trouble from the start, but they told me you were necessary.

What made the black markers dead space